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Rebecka Sepela

rebecka sepela_5524.JPG

I am interested in understanding how specific ionic conductances integrate during pathophysiological and physiological signaling events. To interrogate the broadly applicable mechanisms that underly how ionic flow is modulated and how it drives signaling events, I am currently using the octopus as a model system. The unique touch-taste chemotactile sensation of octopus tightly tethers the peripheral detection of a chemical cue with a neurological behavior.  Additionally, the unique abundance of post-transcriptional RNA modifications found within ion channels permits natural structure-function studies. Together these two instances of evolutionary novelty provide an ideal background for determining how ion channels work, how their function can be modulated, and what happens when their function changes. 

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Miami University


University of California, Davis

2022 - Present

Harvard University

B.S. Biochemistry

Departmental Honors, Magna Cum Laude

Dr. Ann Hagerman Lab

PhD in Biochemistry, Molecular, Cellular, & Developmental Biology

NIH T-32 Trainee in Molecular and Cellular Biology

NIH F-31 NRSA Predoctoral Fellow

NIH NRSA Postdoctoral Fellow

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